Hypoxia and EGF Stimulation Regulate VEGF Expression in Human Glioblastoma Multiforme (GBM) Cells by Differential Regulation of the PI3K/Rho-GTPase and MAPK Pathways

Glioblastoma multiforme (GBM) is one of the most common and deadly cancers of the central nervous system (CNS). It is characterized by the presence of hypoxic regions, especially in the core, leading to an increase in vascularity. This increased vascularization is driven by the expression of the maj...

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Detalles Bibliográficos
Autores principales: Nicolas, Samer, Abdellatef, Sandra, Haddad, Maria Al, Fakhoury, Isabelle, El-Sibai, Mirvat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912653/
https://www.ncbi.nlm.nih.gov/pubmed/31698752
http://dx.doi.org/10.3390/cells8111397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912653/
https://www.ncbi.nlm.nih.gov/pubmed/31698752
http://dx.doi.org/10.3390/cells8111397

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