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HIF1α-Dependent Metabolic Signals Control the Differentiation of Follicular Helper T Cells

Follicular helper T (T(FH)) cells are critical for germinal center (GC) formation and are responsible for effective B cell-mediated immunity; metabolic signaling is an important regulatory mechanism for the differentiation of T(FH) cells. However, the precise roles of hypoxia inducible factor (HIF)...

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Detalles Bibliográficos
Autores principales: Dong, Lin, He, Ying, Zhou, Shuping, Cao, Yejin, Li, Yan, Bi, Yujing, Liu, Guangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912655/
https://www.ncbi.nlm.nih.gov/pubmed/31744227
http://dx.doi.org/10.3390/cells8111450