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Hepatitis C Virus Downregulates Core Subunits of Oxidative Phosphorylation, Reminiscent of the Warburg Effect in Cancer Cells

Hepatitis C Virus (HCV) mainly infects liver hepatocytes and replicates its single-stranded plus strand RNA genome exclusively in the cytoplasm. Viral proteins and RNA interfere with the host cell immune response, allowing the virus to continue replication. Therefore, in about 70% of cases, the vira...

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Detalles Bibliográficos
Autores principales: Gerresheim, Gesche K., Roeb, Elke, Michel, Audrey M., Niepmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912740/
https://www.ncbi.nlm.nih.gov/pubmed/31717433
http://dx.doi.org/10.3390/cells8111410