MLL-Rearranged Acute Leukemia with t(4;11)(q21;q23)—Current Treatment Options. Is There a Role for CAR-T Cell Therapy?

The MLL (mixed-lineage leukemia) gene, located on chromosome 11q23, is involved in chromosomal translocations in a subtype of acute leukemia, which represents approximately 10% of acute lymphoblastic leukemia and 2.8% of acute myeloid leukemia cases. These translocations form fusions with various ge...

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Detalles Bibliográficos
Autores principales: Britten, Oliver, Ragusa, Denise, Tosi, Sabrina, Mostafa Kamel, Yasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912830/
https://www.ncbi.nlm.nih.gov/pubmed/31671855
http://dx.doi.org/10.3390/cells8111341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912830/
https://www.ncbi.nlm.nih.gov/pubmed/31671855
http://dx.doi.org/10.3390/cells8111341

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