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Heavy Water (D(2)O) Containing Preservation Solution Reduces Hepatic Cold Preservation and Reperfusion Injury in an Isolated Perfused Rat Liver (IPRL) Model

Background: Heavy water (D(2)O) has many biological effects due to the isotope effect of deuterium. We previously reported the efficacy of D(2)O containing solution (Dsol) in the cold preservation of rat hearts. Here, we evaluated whether Dsol reduced hepatic cold preservation and reperfusion injury...

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Detalles Bibliográficos
Autores principales: Shimada, Shingo, Fukai, Moto, Shibata, Kengo, Sakamoto, Sodai, Wakayama, Kenji, Ishikawa, Takahisa, Kawamura, Norio, Fujiyoshi, Masato, Shimamura, Tsuyoshi, Taketomi, Akinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912838/
https://www.ncbi.nlm.nih.gov/pubmed/31683811
http://dx.doi.org/10.3390/jcm8111818