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Radiographic appearance of leptomeningeal disease in patients with EGFR-mutated non-small-cell lung carcinoma treated with tyrosine kinase inhibitors: a case series

EGFR is frequently mutated in non-small-cell lung carcinomas (NSCLCs). Clinically available tyrosine kinase inhibitors (TKIs) are effective in treating EGFR-mutant NSCLC. In this case series, we present five patients with TKI-treated EGFR-mutated NSCLC who developed leptomeningeal disease (LMD) lack...

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Detalles Bibliográficos
Autores principales: Sener, Ugur, Matin, Nassim, Yu, Helena, Lin, Andrew, Yang, T Jonathan, Malani, Rachna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912846/
https://www.ncbi.nlm.nih.gov/pubmed/31777268
http://dx.doi.org/10.2217/cns-2019-0010