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Early white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder

BACKGROUND: Autism spectrum disorder (ASD) is prevalent in tuberous sclerosis complex (TSC), occurring in approximately 50% of patients, and is hypothesized to be caused by disruption of neural circuits early in life. Tubers, or benign hamartomas distributed stochastically throughout the brain, are...

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Detalles Bibliográficos
Autores principales: Prohl, Anna K., Scherrer, Benoit, Tomas-Fernandez, Xavier, Davis, Peter E., Filip-Dhima, Rajna, Prabhu, Sanjay P., Peters, Jurriaan M., Bebin, E. Martina, Krueger, Darcy A., Northrup, Hope, Wu, Joyce Y., Sahin, Mustafa, Warfield, Simon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912944/
https://www.ncbi.nlm.nih.gov/pubmed/31838998
http://dx.doi.org/10.1186/s11689-019-9293-x