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Maternally inherited coronary heart disease is associated with a novel mitochondrial tRNA mutation
BACKGROUND: Coronary heart disease (CHD) is the most common cause of mortality globally, yet mitochondrial genetic mutations associated with CHD development remain incompletely understood. METHODS: The subjects from three Chinese families with LHON underwent clinical, genetic, molecular, and biochem...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912950/ https://www.ncbi.nlm.nih.gov/pubmed/31842766 http://dx.doi.org/10.1186/s12872-019-01284-4 |