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Severe Hypouricemia Impairs Endothelium‐Dependent Vasodilatation and Reduces Blood Pressure in Healthy Young Men: A Randomized, Placebo‐Controlled, and Crossover Study

BACKGROUND: Uric acid (UA) is a plasmatic antioxidant that has possible effects on blood pressure. The effects of UA on endothelial function are unclear. We hypothesize that endothelial function is not impaired unless significant UA depletion is achieved through selective xanthine oxidase inhibition...

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Detalles Bibliográficos
Autores principales: De Becker, Benjamin, Coremans, Catherine, Chaumont, Martin, Delporte, Cédric, Van Antwerpen, Pierre, Franck, Thierry, Rousseau, Alexandre, Zouaoui Boudjeltia, Karim, Cullus, Pierre, van de Borne, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912967/
https://www.ncbi.nlm.nih.gov/pubmed/31752638
http://dx.doi.org/10.1161/JAHA.119.013130