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Attenuation of Angiotensin II–Induced Hypertension in BubR1 Low‐Expression Mice Via Repression of Angiotensin II Receptor 1 Overexpression

BACKGROUND: Angiotensin II (Ang II) can cause hypertension and tissue impairment via AGTR1 (Ang II receptor type 1), particularly in renal proximal tubule cells, and can cause DNA damage in renal cells via nicotinamide adenine dinucleotide phosphate oxidase. BubR1 (budding uninhibited by benzimidazo...

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Detalles Bibliográficos
Autores principales: Aoyagi, Yukihiko, Furuyama, Tadashi, Inoue, Kentaro, Matsuda, Daisuke, Matsubara, Yutaka, Okahara, Arihide, Ago, Tetsuro, Nakashima, Yutaka, Mori, Masaki, Matsumoto, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912983/
https://www.ncbi.nlm.nih.gov/pubmed/31787052
http://dx.doi.org/10.1161/JAHA.118.011911