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Spatiotemporal development of spinal neuronal and glial populations in the Ts65Dn mouse model of Down syndrome

BACKGROUND: Down syndrome (DS), caused by the triplication of chromosome 21, results in a constellation of clinical features including changes in intellectual and motor function. Although altered neural development and function have been well described in people with DS, few studies have investigate...

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Detalles Bibliográficos
Autores principales: Aziz, Nadine M., Klein, Jenny A., Brady, Morgan R., Olmos-Serrano, Jose Luis, Gallo, Vittorio, Haydar, Tarik F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913030/
https://www.ncbi.nlm.nih.gov/pubmed/31839007
http://dx.doi.org/10.1186/s11689-019-9294-9