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RNA-seq Reveals Dysregulation of Novel Melanocyte Genes upon Oxidative Stress: Implications in Vitiligo Pathogenesis

Oxidative stress is known to induce melanocyte death, but the underlying mechanisms are incompletely understood. To identify oxidative stress-induced global gene expression changes in melanocytes, we treated PIG1 melanocytes with H(2)O(2) in a dose- and time-dependent manner and performed RNA-seq. T...

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Detalles Bibliográficos
Autores principales: Sastry, Konduru Seetharama, Naeem, Haroon, Mokrab, Younes, Chouchane, Aouatef Ismail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913168/
https://www.ncbi.nlm.nih.gov/pubmed/31871544
http://dx.doi.org/10.1155/2019/2841814