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Heterozygous Disruption of Beclin 1 Alleviates Zinc Oxide Nanoparticles-Induced Disturbance of Cholesterol Biosynthesis in Mouse Liver

PURPOSE: Liver is regarded as one of the primary target organs for zinc oxide nanoparticles (ZnONPs) toxicity. Since liver represents the leading site for de novo cholesterol biosynthesis in mammals, the injuries of liver could result in the disruption of cholesterol biosynthesis. In this study, we...

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Detalles Bibliográficos
Autores principales: Liu, Xuemei, Wang, Bin, Jiang, Xuejun, Zhang, Jun, Tang, Qianghu, Zhang, Yujia, Qin, Xia, Chen, Chengzhi, Zou, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913297/
https://www.ncbi.nlm.nih.gov/pubmed/31849474
http://dx.doi.org/10.2147/IJN.S224179