Molecular Requirements for the Expression of Antiplatelet Effects by Synthetic Structural Optimized Analogues of the Anticancer Drugs Imatinib and Nilotinib

BACKGROUND: Platelets play important roles in cancer progression and metastasis, as well as in cancer-associated thrombosis (CAT). Tyrosine kinases are implicated in several intracellular signaling pathways involved in tumor biology, thus tyrosine kinase inhibitors (TKIs) represent an important clas...

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Detalles Bibliográficos
Autores principales: Pantazi, Despoina, Ntemou, Nikoleta, Brentas, Alexios, Alivertis, Dimitrios, Skobridis, Konstantinos, Tselepis, Alexandros D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913343/
https://www.ncbi.nlm.nih.gov/pubmed/31849454
http://dx.doi.org/10.2147/DDDT.S211907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913343/
https://www.ncbi.nlm.nih.gov/pubmed/31849454
http://dx.doi.org/10.2147/DDDT.S211907

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