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Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities

Influenza is an acute respiratory infection causing high morbidity and mortality in annual outbreaks worldwide. Antiviral drugs are limited and pose the risk of resistance development, calling for new treatment options. IFN-α subtypes are immune-stimulatory cytokines with strong antiviral activities...

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Detalles Bibliográficos
Autores principales: Matos, Aline da Rocha, Wunderlich, Katharina, Schloer, Sebastian, Schughart, Klaus, Geffers, Robert, Seders, Martine, de Witt, Marlous, Christersson, Anmari, Wiewrodt, Rainer, Wiebe, Karsten, Barth, Peter, Hocke, Andreas, Hippenstiel, Stefan, Hönzke, Katja, Dittmer, Ulf, Sutter, Kathrin, Rescher, Ursula, Rodionycheva, Svetlana, Matera, Nicoletta, Ludwig, Stephan, Brunotte, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913622/
https://www.ncbi.nlm.nih.gov/pubmed/31826721
http://dx.doi.org/10.1080/22221751.2019.1698271