Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation

Pursuing on our efforts toward searching for efficient hCA IX and hCA XII inhibitors, herein we report the design and synthesis of new sets of benzofuran-based sulphonamides (4a,b, 5a,b, 9a–c, and 10a–d), featuring the zinc anchoring benzenesulfonamide moiety linked to a benzofuran tail via a hydraz...

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Detalles Bibliográficos
Autores principales: Abdelrahman, Mohamed A., Eldehna, Wagdy M., Nocentini, Alessio, Ibrahim, Hany S., Almahli, Hadia, Abdel-Aziz, Hatem A., Abou-Seri, Sahar M., Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913630/
https://www.ncbi.nlm.nih.gov/pubmed/31809607
http://dx.doi.org/10.1080/14756366.2019.1697250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913630/
https://www.ncbi.nlm.nih.gov/pubmed/31809607
http://dx.doi.org/10.1080/14756366.2019.1697250

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