Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord

Commissural axons initially respond to attractive signals at the midline, but once they cross, they become sensitive to repulsive cues. This switch prevents axons from re-entering the midline. In insects and mammals, negative regulation of Roundabout (Robo) receptors prevents premature response to t...

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Detalles Bibliográficos
Autores principales: Gorla, Madhavi, Santiago, Celine, Chaudhari, Karina, Layman, Awo Akosua Kesewa, Oliver, Paula M., Bashaw, Greg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913780/
https://www.ncbi.nlm.nih.gov/pubmed/30893602
http://dx.doi.org/10.1016/j.celrep.2019.02.080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913780/
https://www.ncbi.nlm.nih.gov/pubmed/30893602
http://dx.doi.org/10.1016/j.celrep.2019.02.080

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