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The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability

Ubiquitin-specific protease (USP) 6 is a hominoid deubiquitinating enzyme previously implicated in intellectual disability and autism spectrum disorder. Although these findings link USP6 to higher brain function, potential roles for USP6 in cognition have not been investigated. Here, we report that...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zeng, Fanwei, Ma, Xuehai, Zhu, Lin, Xu, Qiang, Zeng, Yuzhe, Gao, Yue, Li, Guilin, Guo, Tiantian, Zhang, Haibin, Tang, Xiaoyan, Wang, Ziqiang, Ye, Zesen, Zheng, Liangkai, Zhang, Hongfeng, Zheng, Qiuyang, Li, Kunping, Lu, Jinfang, Qi, Xueting, Luo, Hong, Zhang, Xian, Wang, Zhanxiang, Zhou, Yulin, Yao, Yi, Ke, Rongqin, Zhou, Ying, Liu, Yan, Sun, Hao, Huang, Timothy, Shao, Zhicheng, Xu, Huaxi, Wang, Xin
التنسيق: Online مقال نص
اللغة:English
منشور في: Public Library of Science 2019
الموضوعات:
الوصول للمادة أونلاين:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913916/
https://www.ncbi.nlm.nih.gov/pubmed/31841517
http://dx.doi.org/10.1371/journal.pbio.3000525