The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability

Ubiquitin-specific protease (USP) 6 is a hominoid deubiquitinating enzyme previously implicated in intellectual disability and autism spectrum disorder. Although these findings link USP6 to higher brain function, potential roles for USP6 in cognition have not been investigated. Here, we report that...

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Detalles Bibliográficos
Autores principales: Zeng, Fanwei, Ma, Xuehai, Zhu, Lin, Xu, Qiang, Zeng, Yuzhe, Gao, Yue, Li, Guilin, Guo, Tiantian, Zhang, Haibin, Tang, Xiaoyan, Wang, Ziqiang, Ye, Zesen, Zheng, Liangkai, Zhang, Hongfeng, Zheng, Qiuyang, Li, Kunping, Lu, Jinfang, Qi, Xueting, Luo, Hong, Zhang, Xian, Wang, Zhanxiang, Zhou, Yulin, Yao, Yi, Ke, Rongqin, Zhou, Ying, Liu, Yan, Sun, Hao, Huang, Timothy, Shao, Zhicheng, Xu, Huaxi, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913916/
https://www.ncbi.nlm.nih.gov/pubmed/31841517
http://dx.doi.org/10.1371/journal.pbio.3000525

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