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New insights into intranuclear inclusions in thyroid carcinoma: Association with autophagy and with BRAF(V600E) mutation

BACKGROUND: Intranuclear inclusions (NI) in normal and neoplastic tissues have been known for years, representing one of the diagnostic criteria for papillary thyroid carcinoma (PTC). BRAF activation is involved among others in autophagy. NI in hepatocellular carcinoma contain autophagy-associated p...

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Detalles Bibliográficos
Autores principales: Schwertheim, Suzan, Theurer, Sarah, Jastrow, Holger, Herold, Thomas, Ting, Saskia, Westerwick, Daniela, Bertram, Stefanie, Schaefer, Christoph M., Kälsch, Julia, Baba, Hideo A., Schmid, Kurt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913918/
https://www.ncbi.nlm.nih.gov/pubmed/31841566
http://dx.doi.org/10.1371/journal.pone.0226199