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Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments

The treatment of glioblastoma is challenging for the clinician, due to its chemotherapeutic resistance. Recent findings suggest that targeting glioblastoma using anti-cancer natural polyphenols is a promising strategy. In this context, curcumin and berberine have been shown to have potent anti-cance...

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Detalles Bibliográficos
Autores principales: Maiti, Panchanan, Plemmons, Alexandra, Dunbar, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6913937/
https://www.ncbi.nlm.nih.gov/pubmed/31841506
http://dx.doi.org/10.1371/journal.pone.0225660