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Developmental Rewiring between Cerebellar Climbing Fibers and Purkinje Cells Begins with Positive Feedback Synapse Addition

During postnatal development, cerebellar climbing fibers alter their innervation strengths onto supernumerary Purkinje cell targets, generating a one-to-few connectivity pattern in adulthood. To get insight about the processes responsible for this remapping, we reconstructed serial electron microsco...

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Detalles Bibliográficos
Autores principales: Wilson, Alyssa Michelle, Schalek, Richard, Suissa-Peleg, Adi, Jones, Thouis R., Knowles-Barley, Seymour, Pfister, Hanspeter, Lichtman, Jeff William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914268/
https://www.ncbi.nlm.nih.gov/pubmed/31775050
http://dx.doi.org/10.1016/j.celrep.2019.10.081