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Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry
The lenticular fiber cells are comprised of extremely long-lived proteins while still maintaining an active biochemical state. Dysregulation of these activities has been implicated in diseases such as age-related cataracts. However, the lenticular protein dynamics underlying health and disease is un...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914337/ https://www.ncbi.nlm.nih.gov/pubmed/31820737 http://dx.doi.org/10.7554/eLife.50170 |