Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy

Appropriate regulation of autophagy is crucial for clearing toxic proteins from cells. Defective autophagy results in accumulation of toxic protein aggregates that detrimentally affect cellular function and organismal survival. Here, we report that the microRNA miR-1 regulates the autophagy pathway...

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Detalles Bibliográficos
Autores principales: Nehammer, Camilla, Ejlerskov, Patrick, Gopal, Sandeep, Handley, Ava, Ng, Leelee, Moreira, Pedro, Lee, Huikyong, Issazadeh-Navikas, Shohreh, Rubinsztein, David C, Pocock, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914338/
https://www.ncbi.nlm.nih.gov/pubmed/31799933
http://dx.doi.org/10.7554/eLife.49930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914338/
https://www.ncbi.nlm.nih.gov/pubmed/31799933
http://dx.doi.org/10.7554/eLife.49930

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