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A Scalable CURE Using a CRISPR/Cas9 Fluorescent Protein Knock-In Strategy in Caenorhabditis elegans

Genome editing with CRISPR/Cas9 technology has advanced from the lab bench to clinical application with multiple trials underway. This article introduces a course-based undergraduate experience (CURE) combining CRISPR/Cas9 genome editing (using a modified two-plasmid system) and the animal model Cae...

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Detalles Bibliográficos
Autores principales: Hastie, Eric, Sellers, Ryan, Valan, Bruno, Sherwood, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914349/
https://www.ncbi.nlm.nih.gov/pubmed/31890079
http://dx.doi.org/10.1128/jmbe.v20i3.1847