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MYSM1-AR complex-mediated repression of Akt/c-Raf/GSK-3β signaling impedes castration-resistant prostate cancer growth

Epigenetic alterations that lead to dysregulated gene expression in the progression of castration-resistant prostate cancer (CRPC) remain elusive. Here, we investigated the role of histone deubiquitinase MYSM1 in the pathogenesis of prostate cancer (PCa). Tissues and public datasets of PCa were eval...

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Detalles Bibliográficos
Autores principales: Sun, Jinbo, Hu, Xiangnan, Gao, Yongheng, Tang, Qisheng, Zhao, Zhining, Xi, Wenjin, Yang, Fan, Zhang, Wei, Song, Yue, Song, Bin, Wang, Tao, Wang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914400/
https://www.ncbi.nlm.nih.gov/pubmed/31761786
http://dx.doi.org/10.18632/aging.102482