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MYSM1-AR complex-mediated repression of Akt/c-Raf/GSK-3β signaling impedes castration-resistant prostate cancer growth
Epigenetic alterations that lead to dysregulated gene expression in the progression of castration-resistant prostate cancer (CRPC) remain elusive. Here, we investigated the role of histone deubiquitinase MYSM1 in the pathogenesis of prostate cancer (PCa). Tissues and public datasets of PCa were eval...
Autores principales: | Sun, Jinbo, Hu, Xiangnan, Gao, Yongheng, Tang, Qisheng, Zhao, Zhining, Xi, Wenjin, Yang, Fan, Zhang, Wei, Song, Yue, Song, Bin, Wang, Tao, Wang, He |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914400/ https://www.ncbi.nlm.nih.gov/pubmed/31761786 http://dx.doi.org/10.18632/aging.102482 |
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