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Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia

Pericytes, important elements of the blood-brain barrier (BBB), play critical roles in maintaining BBB integrity and modulating hemostasis, angiogenesis, inflammation and phagocytic function. We investigated whether pericytes are involved in the recombinant tissue plasminogen activator (rt-PA)-induc...

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Detalles Bibliográficos
Autores principales: Yang, Eryan, Cai, Ying, Yao, Xiuhua, Liu, Ji, Wang, Qixue, Jin, Weili, Wu, Qiaoli, Fan, Weijia, Qiu, Lina, Kang, Chunsheng, Wu, Jialing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914411/
https://www.ncbi.nlm.nih.gov/pubmed/31740626
http://dx.doi.org/10.18632/aging.102431