Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice

The aging brain with mitochondrial dysfunction and a reduced adenosine 5’-triphosphate (ATP) has been implicated in the onset and progression of β-Amyloid (Aβ)-induced neuronal toxicity in AD. To unravel the function of ATP and the underlying mechanisms on AD development, APP/PS1 double transgenic m...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Lizhi, Xu, Shicheng, Wu, Tong, Shao, Yijia, Luo, Li, Zhou, Lingqi, Ou, Shanshan, Tang, Hai, Huang, Wenhua, Guo, Kaihua, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914425/
https://www.ncbi.nlm.nih.gov/pubmed/31744937
http://dx.doi.org/10.18632/aging.102451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914425/
https://www.ncbi.nlm.nih.gov/pubmed/31744937
http://dx.doi.org/10.18632/aging.102451

Ejemplares similares