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Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice

The aging brain with mitochondrial dysfunction and a reduced adenosine 5’-triphosphate (ATP) has been implicated in the onset and progression of β-Amyloid (Aβ)-induced neuronal toxicity in AD. To unravel the function of ATP and the underlying mechanisms on AD development, APP/PS1 double transgenic m...

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Detalles Bibliográficos
Autores principales:	Chen, Lizhi, Xu, Shicheng, Wu, Tong, Shao, Yijia, Luo, Li, Zhou, Lingqi, Ou, Shanshan, Tang, Hai, Huang, Wenhua, Guo, Kaihua, Xu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914425/ https://www.ncbi.nlm.nih.gov/pubmed/31744937 http://dx.doi.org/10.18632/aging.102451

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