PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades

Doxorubicin (DOX) is a widely used and potent anticancer agent, but DOX dose-dependently induced cardiotoxicity greatly limits its use in clinic. Pterostilbene, a natural analog of resveratrol, is a known antioxidant and exerts myocardial protection. The present study explored the action and detaile...

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Detalles Bibliográficos
Autores principales: Liu, Dong, Ma, Zhiqiang, Xu, Liqun, Zhang, Xiaoyan, Qiao, Shubin, Yuan, Jiansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914429/
https://www.ncbi.nlm.nih.gov/pubmed/31733141
http://dx.doi.org/10.18632/aging.102418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914429/
https://www.ncbi.nlm.nih.gov/pubmed/31733141
http://dx.doi.org/10.18632/aging.102418

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