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p62-DNA-encoding plasmid reverts tumor grade, changes tumor stroma, and enhances anticancer immunity

Previously, we reported that the administration of a p62/SQSTM1-encoding plasmid demonstrates high safety and signs of clinical benefits for human cancer patients. The treatment also suppressed tumor growth and metastasis in dogs and mouse models. Here we investigated some mechanistic aspects of the...

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Detalles Bibliográficos
Autores principales: Venanzi, Franco M., Gabai, Vladimir, Mariotti, Francesca, Magi, Gian Enrico, Vullo, Cecilia, Sufianov, Albert A., Kolesnikov, Sergey I., Shneider, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914433/
https://www.ncbi.nlm.nih.gov/pubmed/31754084
http://dx.doi.org/10.18632/aging.102486