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p62-DNA-encoding plasmid reverts tumor grade, changes tumor stroma, and enhances anticancer immunity
Previously, we reported that the administration of a p62/SQSTM1-encoding plasmid demonstrates high safety and signs of clinical benefits for human cancer patients. The treatment also suppressed tumor growth and metastasis in dogs and mouse models. Here we investigated some mechanistic aspects of the...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914433/ https://www.ncbi.nlm.nih.gov/pubmed/31754084 http://dx.doi.org/10.18632/aging.102486 |