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Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury

Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections (UTIs), inducing acute pyelonephritis and may result in permanent renal scarring and failure. Alpha-hemolysin (HlyA), a key UPEC toxin, causes serious tissue damage; however, the mechanism through which HlyA induc...

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Detalles Bibliográficos
Autores principales: Wang, Changying, Li, Qianqian, Lv, Junqiang, Sun, Xuan, Cao, Yang, Yu, Kaiyuan, Miao, Chunhui, Zhang, Zhi-Song, Yao, Zhi, Wang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914670/
https://www.ncbi.nlm.nih.gov/pubmed/31719643
http://dx.doi.org/10.1038/s41385-019-0225-6