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Clinical Relevance of Genetic Analysis in Patients With Pituitary Adenomas: A Systematic Review

Pituitary adenomas (PA) are amongst the most prevalent intracranial tumors, causing complications by hormonal overproduction or deficiency and tumor mass effects, with 95% of cases occurring sporadically. Associated germline mutations (AIP, MEN1, CDKN1B, PRKAR1A, SDHx) and Xq26.3 microduplications a...

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Detalles Bibliográficos
Autores principales: van den Broek, Medard F. M., van Nesselrooij, Bernadette P. M., Verrijn Stuart, Annemarie A., van Leeuwaarde, Rachel S., Valk, Gerlof D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914701/
https://www.ncbi.nlm.nih.gov/pubmed/31920960
http://dx.doi.org/10.3389/fendo.2019.00837