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Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins

Many traits vary among isogenic individuals in homogeneous environments. In microbes, plants and animals, variation in the protein chaperone system affects many such traits. In the animal model C. elegans, the expression level of hsp-16.2 chaperone biomarkers correlates with or predicts the penetran...

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Detalles Bibliográficos
Autores principales: Burnaevskiy, Nikolay, Sands, Bryan, Yun, Soo, Tedesco, Patricia M., Johnson, Thomas E., Kaeberlein, Matt, Brent, Roger, Mendenhall, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914778/
https://www.ncbi.nlm.nih.gov/pubmed/31844058
http://dx.doi.org/10.1038/s41467-019-13664-7