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Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins
Many traits vary among isogenic individuals in homogeneous environments. In microbes, plants and animals, variation in the protein chaperone system affects many such traits. In the animal model C. elegans, the expression level of hsp-16.2 chaperone biomarkers correlates with or predicts the penetran...
Autores principales: | Burnaevskiy, Nikolay, Sands, Bryan, Yun, Soo, Tedesco, Patricia M., Johnson, Thomas E., Kaeberlein, Matt, Brent, Roger, Mendenhall, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914778/ https://www.ncbi.nlm.nih.gov/pubmed/31844058 http://dx.doi.org/10.1038/s41467-019-13664-7 |
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