Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids

Human cerebral malaria (HCM), a severe encephalopathy associated with Plasmodium falciparum infection, has a 20–30% mortality rate and predominantly affects African children. The mechanisms mediating HCM-associated brain injury are difficult to study in human subjects, highlighting the urgent need f...

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Detalles Bibliográficos
Autores principales: Harbuzariu, Adriana, Pitts, Sidney, Cespedes, Juan Carlos, Harp, Keri Oxendine, Nti, Annette, Shaw, Andrew P., Liu, Mingli, Stiles, Jonathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914785/
https://www.ncbi.nlm.nih.gov/pubmed/31844087
http://dx.doi.org/10.1038/s41598-019-55631-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914785/
https://www.ncbi.nlm.nih.gov/pubmed/31844087
http://dx.doi.org/10.1038/s41598-019-55631-8

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