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Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids
Human cerebral malaria (HCM), a severe encephalopathy associated with Plasmodium falciparum infection, has a 20–30% mortality rate and predominantly affects African children. The mechanisms mediating HCM-associated brain injury are difficult to study in human subjects, highlighting the urgent need f...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914785/ https://www.ncbi.nlm.nih.gov/pubmed/31844087 http://dx.doi.org/10.1038/s41598-019-55631-8 |