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Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
The human genetic factors that affect resistance to infectious disease are poorly understood. Here we report a genome-wide association study in 17,000 severe malaria cases and population controls from 11 countries, informed by sequencing of family trios and by direct typing of candidate loci in an a...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914791/ https://www.ncbi.nlm.nih.gov/pubmed/31844061 http://dx.doi.org/10.1038/s41467-019-13480-z |