ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress

Maintaining stability of replication forks is important for genomic integrity. However, it is not clear how replisome proteins contribute to fork stability under replication stress. Here, we report that ATAD5, a PCNA unloader, plays multiple functions at stalled forks including promoting its restart...

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Detalles Bibliográficos
Autores principales: Park, Su Hyung, Kang, Nalae, Song, Eunho, Wie, Minwoo, Lee, Eun A., Hwang, Sunyoung, Lee, Deokjae, Ra, Jae Sun, Park, In Bae, Park, Jieun, Kang, Sukhyun, Park, Jun Hong, Hohng, Sungchul, Lee, Kyoo-young, Myung, Kyungjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914801/
https://www.ncbi.nlm.nih.gov/pubmed/31844045
http://dx.doi.org/10.1038/s41467-019-13667-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914801/
https://www.ncbi.nlm.nih.gov/pubmed/31844045
http://dx.doi.org/10.1038/s41467-019-13667-4

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