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Spinal Cord Metabolic Signatures in Models of Fast- and Slow-Progressing SOD1(G93A) Amyotrophic Lateral Sclerosis

The rate of disease progression in amyotrophic lateral sclerosis (ALS) is highly variable, even between patients with the same genetic mutations. Metabolic alterations may affect disease course variability in ALS patients, but challenges in identifying the preclinical and early phases of the disease...

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Detalles Bibliográficos
Autores principales: Valbuena, Gabriel N., Cantoni, Lavinia, Tortarolo, Massimo, Bendotti, Caterina, Keun, Hector C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914819/
https://www.ncbi.nlm.nih.gov/pubmed/31920474
http://dx.doi.org/10.3389/fnins.2019.01276