Cargando…

Spinal Cord Metabolic Signatures in Models of Fast- and Slow-Progressing SOD1(G93A) Amyotrophic Lateral Sclerosis

The rate of disease progression in amyotrophic lateral sclerosis (ALS) is highly variable, even between patients with the same genetic mutations. Metabolic alterations may affect disease course variability in ALS patients, but challenges in identifying the preclinical and early phases of the disease...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valbuena, Gabriel N., Cantoni, Lavinia, Tortarolo, Massimo, Bendotti, Caterina, Keun, Hector C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914819/ https://www.ncbi.nlm.nih.gov/pubmed/31920474 http://dx.doi.org/10.3389/fnins.2019.01276

Ejemplares similares

Altered Metabolic Profiles Associate with Toxicity in SOD1(G93A) Astrocyte-Neuron Co-Cultures
por: Valbuena, Gabriel N., et al.
Publicado: (2017)

Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis
por: Valbuena, Gabriel N., et al.
Publicado: (2015)

P2X7 activation enhances skeletal muscle metabolism and regeneration in SOD1G93A mouse model of amyotrophic lateral sclerosis
por: Fabbrizio, Paola, et al.
Publicado: (2019)

Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice
por: Banerjee, Rebecca, et al.
Publicado: (2008)

Early gene expression changes in spinal cord from SOD1(G93A) Amyotrophic Lateral Sclerosis animal model
por: de Oliveira, Gabriela P., et al.
Publicado: (2013)

Neuroprotective Effect of Bexarotene in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
por: Riancho, Javier, et al.
Publicado: (2015)

Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1(G93A) mice
por: Scaricamazza, Silvia, et al.
Publicado: (2022)

Comparing therapeutic modulators of the SOD1 G93A Amyotrophic Lateral Sclerosis mouse pathophysiology
por: Lee, Albert J. B., et al.
Publicado: (2023)

Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes: IMPLICATIONS FOR DISEASE SPREADING AND MOTOR NEURON PATHOLOGY IN AMYOTROPHIC LATERAL SCLEROSIS
por: Basso, Manuela, et al.
Publicado: (2013)

Comparative Magnetic Resonance Imaging and Histopathological Correlates in Two SOD1 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis
por: Caron, Ilaria, et al.
Publicado: (2015)

Lack of Effect of Methylene Blue in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis
por: Lougheed, Rosamond, et al.
Publicado: (2011)

Comparative study of behavioural tests in the SOD1G93A mouse model of amyotrophic lateral sclerosis
por: OLIVÁN, Sara, et al.
Publicado: (2014)

Measuring Neuromuscular Junction Functionality in the SOD1(G93A) Animal Model of Amyotrophic Lateral Sclerosis
por: Rizzuto, Emanuele, et al.
Publicado: (2015)

Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα
por: Tortarolo, Massimo, et al.
Publicado: (2017)

The p97‐Nploc4 ATPase complex plays a role in muscle atrophy during cancer and amyotrophic lateral sclerosis
por: Re Cecconi, Andrea David, et al.
Publicado: (2022)

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis
por: Lee, John D, et al.
Publicado: (2013)

Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
por: Yan, Lina, et al.
Publicado: (2018)

The transcription factor Nurr1 is upregulated in amyotrophic lateral sclerosis patients and SOD1-G93A mice
por: Valsecchi, Valeria, et al.
Publicado: (2020)

MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1(G93A) Motor Neuron of Amyotrophic Lateral Sclerosis
por: Peng, Jialing, et al.
Publicado: (2022)

Targeting autotaxin impacts disease advance in the SOD1‐G93A mouse model of amyotrophic lateral sclerosis
por: Gento‐Caro, Ángela, et al.
Publicado: (2021)

Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice
por: Renzini, Alessandra, et al.
Publicado: (2022)

Different sensorimotor mechanism in fast and slow progression amyotrophic lateral sclerosis
por: Li, Qianwen, et al.
Publicado: (2021)

SOD1 and Amyotrophic Lateral Sclerosis: Mutations and Oligomerization
por: Banci, Lucia, et al.
Publicado: (2008)

Metal-deficient SOD1 in amyotrophic lateral sclerosis
por: Hilton, James B., et al.
Publicado: (2015)

Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1(G93A) Amyotrophic Lateral Sclerosis mouse model
por: Maximino, Jessica R., et al.
Publicado: (2014)

Activation of Phosphotyrosine-Mediated Signaling Pathways in the Cortex and Spinal Cord of SOD1(G93A), a Mouse Model of Familial Amyotrophic Lateral Sclerosis
por: Mallozzi, Cinzia, et al.
Publicado: (2018)

Compensatory Motor Neuron Response to Chromatolysis in the Murine hSOD1(G93A) Model of Amyotrophic Lateral Sclerosis
por: Riancho, Javier, et al.
Publicado: (2014)

Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
por: Novoselov, Sergey S., et al.
Publicado: (2013)

Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice
por: Chen, Dapeng, et al.
Publicado: (2015)

Rosmarinic Acid Alleviates Neurological Symptoms in the G93A-SOD1 Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
por: Seo, Ji-Seon, et al.
Publicado: (2015)

Seeking homeostasis: temporal trends in respiration, oxidation, and calcium in SOD1 G93A Amyotrophic Lateral Sclerosis mice
por: Irvin, Cameron W., et al.
Publicado: (2015)

Histamine Regulates the Inflammatory Profile of SOD1-G93A Microglia and the Histaminergic System Is Dysregulated in Amyotrophic Lateral Sclerosis
por: Apolloni, Savina, et al.
Publicado: (2017)

Cromolyn sodium delays disease onset and is neuroprotective in the SOD1(G93A) Mouse Model of amyotrophic lateral sclerosis
por: Granucci, Eric J., et al.
Publicado: (2019)

Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1(G93A) mice
por: Shapiro, Dillon, et al.
Publicado: (2022)

Caudal–Rostral Progression of Alpha Motoneuron Degeneration in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
por: Kirby, Alastair J., et al.
Publicado: (2022)

Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord
por: Trist, Benjamin G, et al.
Publicado: (2022)

The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis
por: Galbiati, Mariarita, et al.
Publicado: (2012)

Spinal cord homogenates from SOD1 familial amyotrophic lateral sclerosis induce SOD1 aggregation in living cells
por: Pokrishevsky, Edward, et al.
Publicado: (2017)

Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
por: Saccon, Rachele A., et al.
Publicado: (2013)

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis
por: Paré, Bastien, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2fe4qoap9eihu6j89fa6nvko9h