Loss of Dkk-1 in Osteocytes Mitigates Alveolar Bone Loss in Mice With Periodontitis

Background: Periodontitis is a highly prevalent infection-triggered inflammatory disease that results in bone loss. Inflammation causes bone resorption by osteoclasts, and also by suppression of bone formation via increase of Dickkopf-1 (Dkk-1), an inhibitor of Wnt signaling. Here, we tested the hyp...

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Detalles Bibliográficos
Autores principales: Goes, Paula, Dutra, Caio, Lösser, Lennart, Hofbauer, Lorenz C., Rauner, Martina, Thiele, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914827/
https://www.ncbi.nlm.nih.gov/pubmed/31921182
http://dx.doi.org/10.3389/fimmu.2019.02924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914827/
https://www.ncbi.nlm.nih.gov/pubmed/31921182
http://dx.doi.org/10.3389/fimmu.2019.02924

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