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Mechanisms of Immune Activation by c9orf72-Expansions in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders with overlapping pathomechanisms, neurobehavioral features, and genetic etiologies. Individuals diagnosed with either disorder exhibit symptoms within a clinical spectrum. Symptoms of ALS involve ne...

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Detalles Bibliográficos
Autores principales: Trageser, Kyle J., Smith, Chad, Herman, Francis J., Ono, Kenjiro, Pasinetti, Giulio Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914852/
https://www.ncbi.nlm.nih.gov/pubmed/31920478
http://dx.doi.org/10.3389/fnins.2019.01298