Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung

Clinical studies have demonstrated a strong association between both acute toxic exposure and the repetitive, chronic exposure to acetaminophen (APAP) with pulmonary dysfunction. However, the mechanisms underlying this association are unknown. Preclinical reports have demonstrated that significant b...

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Detalles Bibliográficos
Autores principales: Sandoval, Jeryl, Orlicky, David J., Allawzi, Ayed, Butler, Brittany, Ju, Cynthia, Phan, Caroline T., Toston, Roy, De Dios, Robyn, Nguyen, Leanna, McKenna, Sarah, Nozik-Grayck, Eva, Wright, Clyde J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914885/
https://www.ncbi.nlm.nih.gov/pubmed/31885815
http://dx.doi.org/10.1155/2019/7595126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914885/
https://www.ncbi.nlm.nih.gov/pubmed/31885815
http://dx.doi.org/10.1155/2019/7595126

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