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LOX-1, the Common Therapeutic Target in Hypercholesterolemia: A New Perspective of Antiatherosclerotic Action of Aegeline

BACKGROUND: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is the major receptor for oxidized low-density lipoprotein (Ox-LDL) in the aorta of aged rats. Ox-LDL initiates LOX-1 activation in the endothelium of lipid-accumulating sites of both animal and human subjects of hypercholes...

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Detalles Bibliográficos
Autores principales: Singh, Abhilasha, Srinivasan, Ashok Kumar, Chakrapani, Lakshmi Narasimhan, Kalaiselvi, Periandavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914969/
https://www.ncbi.nlm.nih.gov/pubmed/31885819
http://dx.doi.org/10.1155/2019/8285730