Mechanisms of Anthracycline-Enhanced Reactive Oxygen Metabolism in Tumor Cells

In this investigation, we examined the effect of anthracycline antibiotics on oxygen radical metabolism in Ehrlich tumor cells. In tumor microsomes and nuclei, doxorubicin increased superoxide anion production in a dose-dependent fashion that appeared to follow saturation kinetics; the apparent K(m)...

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Detalles Bibliográficos
Autor principal: Doroshow, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914999/
https://www.ncbi.nlm.nih.gov/pubmed/31885826
http://dx.doi.org/10.1155/2019/9474823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914999/
https://www.ncbi.nlm.nih.gov/pubmed/31885826
http://dx.doi.org/10.1155/2019/9474823

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