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Mechanisms of Anthracycline-Enhanced Reactive Oxygen Metabolism in Tumor Cells
In this investigation, we examined the effect of anthracycline antibiotics on oxygen radical metabolism in Ehrlich tumor cells. In tumor microsomes and nuclei, doxorubicin increased superoxide anion production in a dose-dependent fashion that appeared to follow saturation kinetics; the apparent K(m)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914999/ https://www.ncbi.nlm.nih.gov/pubmed/31885826 http://dx.doi.org/10.1155/2019/9474823 |