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Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction

For over 2 decades preimplantation genetic testing (PGT) has been in clinical use to reduce the risk of miscarriage and genetic disease in patients with advanced maternal age and risk of transmitting disease. Recently developed methods of genome-wide genotyping and machine learning algorithms now of...

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Detalles Bibliográficos
Autores principales: Treff, Nathan R., Eccles, Jennifer, Lello, Lou, Bechor, Elan, Hsu, Jeffrey, Plunkett, Kathryn, Zimmerman, Raymond, Rana, Bhavini, Samoilenko, Artem, Hsu, Steven, Tellier, Laurent C. A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915076/
https://www.ncbi.nlm.nih.gov/pubmed/31920964
http://dx.doi.org/10.3389/fendo.2019.00845